产品货号：
Z22983
中文名称：
PDCD4抗体
英文名称：
Anti-PDCD4 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PDCD4 Antibody |
| 指标别名 | H731;Nuclear antigen H731 like;PDCD4;Protein 197/15a |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC |
| 基因名称 | PDCD4 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | PDCD4 antibody was raised against a 19 amino acid synthetic peptide from near the carboxy terminus of human PDCD4.The immunogen is located within the last 50 amino acids of PDCD4. |
| 计算分子量 | 52kDa |
| 成分 | PDCD4 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | PDCD4 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Apoptosis,also known as programmed cell death,plays major roles in development and normal tissue turnover in addition to tumor formation.During this process,the expression patterns of numerous genes are radically altered.One such gene is the programmed cell death protein 4 (PDCD4),whose expression was found to be upregulated in all cell lines following the onset of apoptosis.PDCD4 encodes a tumor suppressor protein whose expression is lost in carcinomas of breast,colon,lung and prostate.It can bind to and inhibit the helicase activity of the eukaryotic translation initiation factor 4A and inhibit the transactivation and transformation mediated by the transcription factor AP-1.The kinase Akt regulates PDCD4 by phosphorylation,decreasing the ability of PDCD4 to interfere with the transactivation of AP-1-responsive promoter by c-Jun.There are two known isoforms of PDCD4. |
| Uniprot ID | Q53EL6 |
| 基因名全称 | Programmed cell death 4 (neoplastic transformation inhibitor) |
| 蛋白名全称 | Programmed cell death 4 (neoplastic transformation inhibitor) |
| 推荐稀释比 | PDCD4 antibody can be used for detection of PDCD4 by Western blot at 0.5 ～ 1μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.Antibody validated:Western Blot in mouse samples and Immunohistochemistry in mouse samples.All other applications and species not yet tested. |
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